Regulatory
Part:BBa_K5378009:Design
Designed by: pan zhao Group: iGEM24_SMU-GDMU-CHINA (2024-09-25)
PtynA
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 12COMPATIBLE WITH RFC[12]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
- 1000COMPATIBLE WITH RFC[1000]
Design Notes
PtynA, the promoter of tynA, is present in the Escherichia coli. It is used to activate the downstream expression to respond to phenylethylamine (PEA). In the presence of the aldehydes, FeaR induces expression from the PtynA promoter.
Source
Escherichia coli.
References
Zeng, J., & Spiro, S. (2013). Finely tuned regulation of the aromatic amine degradation pathway in Escherichia coli. Journal of bacteriology, 195(22), 5141-5150.